Argan Stem Cells

PhytoCellTec™ Argan is the first active ingredient able to protect and revitalise skin stem cells. This not only helps to accelerate the natural skin repair process, but also fights against skin aging from the root and therefore achieves a fresh and radiant appearance.

 

 

 

 

 

PHYTOCELLTEC™ Argán.

PhytoCellTec™ Argan was developed to improve the regenerative capacity of dermal stem cells, achieving a deep rejuvenation of the skin. This active ingredient is based on Argan tree stem cells, one of the oldest tree species in the world. The Argan tree is native to the arid southeast of Morocco and has perfectly adapted to the intense drought and extremely high temperatures characterising that region. Unfortunately, the area where these trees grow has dramatically reduced due to the extensive use of land, so nowadays the remaining Argan tree forests are under UNESCO protection.

 

Adult skin stem cells, dermal stem cells.

The main function of the dermis is providing mechanical support and elasticity to the skin. In order to maintain these functions, healthy skin is submitted to a constant cell renovation, which renews and repairs the dermal connective tissue. New cells are produced to replace the damaged or dead ones.

The main function of the dermis is providing mechanical support and elasticity to the skin. In order to maintain these functions, healthy skin is submitted to a constant cell renovation, which renews and repairs the dermal connective tissue. New cells are produced to replace the damaged or dead ones.

Adult dermal stem cells are responsible for this regenerating process and are found in the dermal papilla of the hair follicle. These cells are differentiated in fibroblasts, which are responsible for the on-going production of extracellular matrix proteins: elastin and collagen. However, as dermal stem cells age, they become less numerous and show a reduced activity. As a consequence, the production of collagen and elastin decreases and skin loses firmness - wrinkles appear. Thus, it is fundamental to protect dermal stem cells and maintain its activity.

 

Vegetal stem cells to protect human skin stemcells.

The activity of stem cells is regulated by specific compounds, epigenetic* factors, among others. Vegetal stem cells also have these epigenetic factors. In vitro studies show that an extract made of vegetal stem cells has a positive influence on the activity of human dermal stem cells.

 

Improving the structure of extracellular matrix structure - reduction of wrinkele depth.

The forearm dermal tissue structure of volunteers was presented by ultrasound before and after PhytoCellTec™ Argan treatment (figure 1). Ultrasound images of the dermis show bright colours, while the so-called subepidermal low-echogenic band (SLEB) produces dark spots. This SLEB is the result of an altered architecture of the dermis which is commonly found in aged and photo-damaged skin. The results clearly show that a 56-day treatment with PhytoCellTec™ Argan reduces SLEB and significantly improves dermal tissue density.

The anti-wrinkle effect of PhytoCellTec™ Argan was proven in a clinical study with 21 volunteers with an average of 49 years old. A cream with 0.4% of PhytoCellTec™ Argan was applied on the outline of the eye over 56 days. The results reveal a reduction in wrinkle depth of a significant 26%.

* Epigenesis f. biol. Theory according to which the features characterising a human being are modelled along its development, without being pre-formed in the germ.

Mibelle Group Biochemistry authorises Argan Oil to use information from its studies about Phytocelltec ™ Argan.

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